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Toxicology
Research laboratories and drug development companies around the world use MSD technology to analyze disease states through the characterization and quantification of biomarkers. We maintain a list of scientific journal articles that describe how MSD assays have been instrumental in providing highly sensitive, quantified, reproducible results.
Enter keywords to search all publications. To see a complete list of publications by research topic, select an area of interest.
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Cytokines & Chemokines (1)
Metabolic Markers (1)
Methods & Technology (1)
Toxicology (29)
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Autoimmune & Inflammation (2)
Cardiovascular Disease (5)
Infectious Diseases (6)
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Toxicology
Results 1 - 25 of 29
Title
Journal
Year
Acute phase response, inflammation and metabolic syndrome biomarkers of Libby asbestos exposure.
Shannahan JH, Alzate O, Winnik WM, Andrews D, Schladweiler MC, Ghio AJ, Gavett SH, Kodavanti UP.
Toxicol Appl Pharmacol.
2012
Comparison of the Diagnostic Accuracy of Di-22:6-Bis(monoacylglycerol)Phosphate and Other Urinary Phospholipids for Drug-Induced Phospholipidosis or Tissue Injury in the Rat.
Thompson KL, Haskins K, Rosenzweig BA, Stewart S, Zhang J, Peters D, Knapton A, Rouse R, Mans D, Colatsky T.
Int J Toxicol.
2012
Surface Sampling of a Dry Aerosol Deposited Ricin.
Edmonds JM, Collett PJ, Brown RL, Mangaya K.
Appl Sci.
2012
(2011) Nephrotoxicity of hexachloro-1:3-butadiene in the male Hanover Wistar rat; correlation of minimal histopathological changes with biomarkers of renal injury.
Swain, A., Turton, J., Scudamore, C., Maguire, D., Pereira, I., Freitas, S., Smyth, R., Munday, M., Stamp, C., Gandhi, M., Sondh, S., Ashall, H., Francis, I., Woodfine, J., Bowles, J., York, M.
J Appl Toxicol.
2011
Chronic Antagonism of the Mineralocorticoid Receptor Ameliorates Hypertension and End Organ Damage in a Rodent Model of Salt-Sensitive Hypertension.
Zhou, X., Crook, M.F., Sharif-Rodriguez, W., Zhu, Y., Ruben, Z., Pan, Y., Urosevic-Price, O., Wang, L., Flattery, A.M., Forrest, G., Szeto, D., Zhao, H., Roy, S., Forrest, M.J.
Clin Exp Hypertens.
2011
Comparison of the course of biomarker changes and kidney injury in a rat model of drug-induced acute kidney injury.
Sasaki, D., Yamada, A., Umeno, H., Kurihara, H., Nakatsuji, S., Fujihira, S., Tsubota, K., Ono, M., Moriguchi, A., Watanabe, K., Seki, J.
Biomarkers.
2011
Agents associated with lung inflammation induce similar responses in NCI-H292 lung epithelial cells.
Newland, N., Richter, A.
Toxicol In Vitro.
2008
Differences in effects on myocardium and mitochondria by angiogenic inhibitors suggest separate mechanisms of cardiotoxicity.
French, K.J., Coatney, R.W., Renninger, J.P., Hu, C.X., Gales, T.L., Zhao, S., Storck, L.M., Davis, C.B., McSurdy-Freed, J., Chen, E., Frazier, K.S.
Toxicol Pathol.
2010
Recommendations to qualify biomarker candidates of drug-induced liver injury.
Ozer, J.S., Chetty, R., Kenna, G., Koppiker, N., Karamjeet, P., Li, D., Palandra, J., Lanevschi, A., Souberbielle, B.E., Ramaiah, S.
Biomark Med.
2010
Comparative profile of commercially available urinary biomarkers in preclinical drug-induced kidney injury and recovery in rats.
Rouse, R.L., Zhang, J., Stewart, S.R., Rosenzweig, B.A., Espandiari, P., Sadrieh, N.K.
Kidney Int.
2010
Veterinary and toxicological applications for the detection of cardiac injury using cardiac troponin.
Serra, M., Papakonstantinou, S., Adamcova, M., O'Brien, P.J.
The Veterinary Journal.
2010
Application of Dolichos biflorus in immunoassay detection of kidney collecting duct biomarkers.
Sourial, S., Searchfield, L., Schuppe-Koistinen, I., Betton, G.R., Riccardi, D., Price, S.A.
Biomarkers.
2010
Applications of a planar electrochemiluminescence platform to support regulated studies of macromolecules: Benefits and limitations in assay range.
Thway, T., Macaraeg, C., Calamba, D., Patel, V., Tsoi, J., Ma, M., Lee, J., Desilva, B.
Pharm Biomed Anal.
2010
Evaluation of the usefulness of urinary biomarkers for nephrotoxicity in rats.
Tonomura, Y., Tsuchiya, N., Torii, M., Uehara, T.
Toxicology.
2010
No increases in biomarkers of genetic damage or pathological changes in heart and brain tissues in male rats administered methylphenidate hydrochloride (Ritalin) for 28 days.
Witt, K.L., Malarkey, D.E., Hobbs, C.A., Davis, J.P., Kissling, G.E., Caspary, W., Travlos, G., Recio, L.
Environ Mol Mutagen.
2010
Antibody protection against botulinum neurotoxin intoxication in mice.
Cheng, L.W., Stanker, L.H., Henderson, T.D. 2nd, Lou, J., Marks, J.D.
Infect Immun.
2009
Application of deadenylase electrochemiluminescence assay for ricin to foods in a plate format.
Cho, C.Y., Keener, W.K., Garber, E.A.
J Food Prot.
2009
Raxibacumab for the Treatment of Inhalational Anthrax
Migone, T.S., Subramanian, G.M., Zhong, J., Healey, L.M., Corey, A., Devalaraja, M., Lo, L., Ullrich, S., Zimmerman, J., Chen, A., Lewis, M., Meister, G., Gillum, K., Sanford, D., Mott, J., Bolmer, S.D.
The New England Journal of Medicine.
2009
Electrochemiluminescent immunoassay for rat skeletal troponin I (Tnni2) in serum.
Sun, D., Hamlin, D., Butterfield, A., Watson, D.E., Smith, H.W.
J Pharmacol Toxicol Methods.
2009
Evaluation of the usefulness of biomarkers for cardiac and skeletal myotoxicity in rats.
Tonomura, Y., Mori, Y., Torii, M., Uehara, T.
Toxicology.
2009
Novel technologies for the discovery and quantitation of biomarkers of toxicity.
Collings, F.B., Vaidya, V.S.
Toxicology.
2008
Detection of ricin in food using electrochemiluminescence-based technology.
Garber, E.A., O'Brien, T.W.
J AOAC Int.
2008
Cardiac troponin is the most effective translational safety biomarker for myocardial injury in cardiotoxicity.
O'Brien, P.J.
Toxicology.
2008
Comparison of an electrochemiluminescence assay in plate format over a colorimetric ELISA, for the detection of ricin B chain (RCA-B).
Guglielmo-Viret, V., Thullier, P.
J Immunol Methods
2007
Urine Biomarkers Predict Acute Kidney Injury and Mortality in Very Low Birth Weight Infants.
Askenazi, D.J., Montesanti, A., Hunley, H., Koralkar, R., Pawar, P., Shuaib, F., Liwo, A., Devarajan, P., Ambalavanan, N.
J Pediatr.
2011
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